Technology Behind Peri-X
Peri-X gel is designed to treat periimplantitis and peri implant mucositis via dismantling the biofilm that causes the disease.
Recurring Inflammatory Conditions: peri-implantitis and peri-implant mucositis are chronic, recurring inflammatory diseases affecting dental implant patients.
Symptoms: Peri-implantitis symptoms include inflammation, bleeding, gum recession, implant mobility, and potential implant failure.
High prevalence rates: 63% for peri-implant mucositis and 20% for peri-implantitis.
Cause: Oral microbial film on exposed teeth and subgingival tissue.
Biofilm Challenge: Conventional bactericidal compounds target live flora but lack effectiveness against biofilm.
The “gold standard” treatment today is still based on mechanical anti-infective approach (scaling and root planing, SRP). The treatment may also include antibiotics, antiseptics, laser/ PDT therapy.
SRP has poor efficacy (~30% failure rate) and requires repetition on a regular basis.
The consensus is that local/topical antiseptics and antibiotic have little effect due to the formed biofilm (that prevents the active pharmaceutical ingredient from penetrating).
- Peri-X addresses a critical issue both to patient and dentist, as dental implants are part of an expensive and lengthy procedure.
- Peri-X is suitable for use by both dentists and hygienists.
Peri-X gel has a unique proprietary composition: Sodium Polyphosphates + N,N-Bis (carboxymethyl)-L-glutamic acid tetrasodium.
Gel: thermo-sensitive formula. Transforms instantly from liquid to gel in contact with 37°C gingiva.
Clinical Success: Demonstrates significant pocket depth reduction within 6 weeks after 1 use.
Developed in collaboration with Prof. David Polak, an esteemed periodontist from Hadassah dental school in HUJI.
The technology is Patent pending and the product is already registered and approved as a medical device.
